CAR-T Cell Engineering

CAR-T cell therapy at ADSCC is used for treating certain types of blood cancers. This therapy is given to patients who have not responded to conventional treatments such as BMT and Chemotherapy.

Some of the advantages of CAR-T cell therapy are:

• It is a personalized treatment that uses the patient’s own cells.
• It can be used to treat certain blood cancers that are resistant to other treatments.
• It has the potential to be a long-term treatment.

CAR-T cell therapy is a special kind of treatment where physicians change a person’s immune system cells, called T cells, to make them better at fighting cancer by giving these cells a special receptor that helps them attach to the tumor, which is the bad part. Then, these changed cells would be ready to attack and destroy the cancer cells.

ADSCC’s physicians withdraw the cells and genetically modify the patient’s immune cells in one of the very few specialized GMP laboratory in the region at ADSCC to gain the possibility of fighting cancer cells in the patient after their intravenous injection.

ADSCC’s CAR-T cell project is designed for the manufacture of adoptive cell therapy targeting specific B-cell3 antigens with the goal of eliminating B-cells and specific B-cell clones that lead to disease. CAR-T cell therapy is undoubtedly leading a revolution in cancer therapy. Recent successes in treating hematologic malignancies with CAR-T cell therapy and the availability of several commercial products have prompted increased interest in cancer immunotherapy. They produce new blood cells and promote growth of new marrow.